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E otciparik masinahikaniwoc(957x562pixels, e irikweckamikak mawtockwemikan:327 kionohwe MIME:image/png)

Ohwe masinahikaniwoc ote otciparin Wikimedia Commons. Matci kotakahik wec kata apatan. Ota masinateriw https://commons.wikimedia.org/wiki/File:DE_landscape.png e irapatanik.

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E witcikemakak
English: Performing multiple rounds of directed evolution is useful not only because a new library of mutants is created in each round but also because each new library uses better mutants as templates. The experiment is analogous to climbing a hill on a 'fitness landscape' where elevation represents the desired property. The goal is to reach the summit, which represents the best achievable mutant. Each round of selection samples mutants on all sides of the starting template (1) and selects the mutant with the highest elevation, thereby climbing the hill. This is repeated until a local summit is reached (2).
Apitc
Ite wetciparik Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge.
Ka ki masihiketc Thomas Shafee

Orocowatcikan

Moi, en tant que détenteur des droits d’auteur sur cette œuvre, je la publie sous la licence suivante :
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ka ki wectatc
Ce fichier est disponible selon les termes de la licence Creative Commons Attribution 4.0 International.
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mekwatc13 Pitcipipon pisimw 2014 à 20:29Masinasowinicic apitc ka meckotcipatakaniwitc 13 Pitcipipon pisimw 2014 à 20:29957 × 562 (327 kio)Evolution and evolvabilityincreased axis title size
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